KLF17

Krueppel-like factor 17 adalah protein yang pada manusia disandi oleh gen KLF17.[4][5] KLF17 merupakan faktor transkripsi yang berperan sebagai penghambat langkah awal dalam metastasis kanker payudara.[6]

KLF17
Pengidentifikasi
AliasKLF17, ZNF393, Zfp393, Kruppel-like factor 17, Kruppel like factor 17, ZLF393
ID eksternalOMIM: 609602 MGI: 2181068 HomoloGene: 12621 GeneCards: KLF17
Lokasi gen (Manusia)
Kr.Kromosom 1 (manusia)[1]
Pita1p34.1Awal44,118,821 bp[1]
Akhir44,135,140 bp[1]
Ortolog
SpesiesManusiaTikus
Entrez

128209

75753

Ensembl

ENSG00000171872

ENSMUSG00000048626

UniProt

Q5JT82

Q8CFA7

RefSeq (mRNA)

NM_173484

NM_029416

RefSeq (protein)

NP_775755

NP_083692

Lokasi (UCSC)Chr 1: 44.12 – 44.14 Mbn/a
Pencarian PubMed[2][3]
Wikidata
Lihat/Sunting ManusiaLihat/Sunting Tikus

Referensi

  1. GRCh38: Ensembl release 89: ENSG00000171872 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Human KLF17 is a new member of the Sp/KLF family of transcription factors". Genomics. 87 (4): 474–82. Apr 2006. doi:10.1016/j.ygeno.2005.12.011. PMID 16460907.
  5. "Entrez Gene: KLF17 Kruppel-like factor 17".
  6. Huang, Qihong; Zhang, Lin; Coukos, George; Katsaros, Dionyssios; Showe, Louise C.; Klein-Szanto, Andres J.; Gimotty, Phyllis A.; Li, Anping; Gumireddy, Kiranmai (2009-11). "KLF17 is a negative regulator of epithelial–mesenchymal transition and metastasis in breast cancer". Nature Cell Biology (dalam bahasa Inggris). 11 (11): 1297–1304. doi:10.1038/ncb1974. ISSN 1476-4679. PMC 2784164. PMID 19801974.
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