SDHC

SDHC
Pengidentifikasi
Alias	SDHC, CYB560, CYBL, PGL3, QPS1, SDH3, succinate dehydrogenase complex subunit C
ID eksternal	OMIM: 602413 MGI: 1913302 HomoloGene: 2256 GeneCards: SDHC
Lokasi gen (Manusia)
Kr.	Kromosom 1 (manusia)[1]
Akhir	161,363,206 bp[1]
Lokasi gen (Tikus)
Kr.	Kromosom 1 (tikus)[2]
Akhir	170,978,172 bp[2]
Ontologi gen
Fungsi molekuler	• electron transfer activity; • oxidoreductase activity, acting on the CH-CH group of donors; • succinate dehydrogenase activity; • heme binding; • metal ion binding; • succinate dehydrogenase (ubiquinone) activity; • ubiquinone binding;
Komponen seluler	• komponen integral membran; • mitochondrial inner membrane; • respiratory chain complex II; • succinate dehydrogenase complex; • mitokondria; • membran; • mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone);
Proses biologis	• aerobic respiration; • Siklus asam sitrat; • mitochondrial electron transport, succinate to ubiquinone; • response to oxidative stress;
	Sumber:Amigo / QuickGO
Ortolog
	6391
	66052
	ENSG00000143252
	ENSMUSG00000058076
	Q99643
	Q9CZB0
	NM_001035511; NM_001035512; NM_001035513; NM_001278172; NM_003001
	NM_025321
	NP_001030588; NP_001030589; NP_001030590; NP_001265101; NP_002992
	NP_079597
	Wikidata
Lihat/Sunting Manusia	Lihat/Sunting Tikus

SDHC merupakan berkas genetik pada kromosom 1 lokasi 1q23.3 dengan ekspresi genetik berupa protein cybL yang merupakan sub-unit C dari suksinat dehidrogenase. Mutasi pada gen ini mengakibatkan paraganglioma.[5]

Rujukan

GRCh38: Ensembl release 89: ENSG00000143252 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000058076 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
(Inggris) "SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-11-05.

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